Methodologies in creating skin substitutes
نویسندگان
چکیده
منابع مشابه
Cultured skin substitutes: a review.
Skin substitutes composed of cultured cells and biopolymers provide alternative materials for study of skin biology and pathology, treatment of skin wounds, safety testing of consumer products, and therapeutic delivery of gene products. Most frequently, substitutes for epidermis consist of cultured keratinocytes and dermal substitutes consist of resorbable biopolymers populated with cultured fi...
متن کاملClinical applications of skin substitutes.
A unique understanding of the components of mammalian skin has led to the development of numerous skin substitutes. These skin substitutes attempt to compensate for functional and physiologic deficits present in damaged tissue. Skin substitutes, when appropriately applied in optimized settings, offer a promising solution to difficult wound management. The body of literature on skin substitutes ...
متن کاملBio-Engineered Skin and Soft Tissue Substitutes
When Policy Topic is covered Breast reconstructive surgery using allogeneic acellular dermal matrix products* (i.e., AlloDerm®, AlloMaxTM, DermaMatrixTM, FlexHD®, GraftJacket®) may be considered medically necessary, when there is insufficient tissue expander or implant coverage by the pectoralis major muscle and additional coverage is required, when there is viable but compromised or thin p...
متن کاملEngineered skin substitutes: practices and potentials.
Wound healing can be problematic in several clinical settings because of massive tissue injury (burns), wound healing deficiencies (chronic wounds), or congenital conditions and diseases. Engineered skin substitutes have been developed to address the medical need for wound coverage and tissue repair. Currently, no engineered skin substitute can replace all of the functions of intact human skin....
متن کاملTissue-Engineered Skin Substitutes - 06/12
Tissue-engineered skin substitutes may be either acellular or cellular. Acellular products (i.e., cadaveric human dermis with cellular material removed) contain a matrix or scaffold composed of materials such as collagen, hyaluronic acid, and fibronectin. Cellular products contain living cells such as fibroblasts and keratinocytes within a matrix. The cells contained within the matrix may be au...
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ژورنال
عنوان ژورنال: Cellular and Molecular Life Sciences
سال: 2016
ISSN: 1420-682X,1420-9071
DOI: 10.1007/s00018-016-2252-8